This invention discloses a hydroxy-morusin compound and a preparation method thereof and applications thereof in preparing a medicine for treatment or prevention of mouth disease and preparing mouth nursing products.本發明披露了一種羥基桑根素(Hydroxy-morusin)化合物,其製備方法,以及其在製備治療或預防口腔疾病的藥物中、和在製備口腔護理用品中的應用。