This invention includes the buccal cavity CARE composition and method in order to obstruct the growth and formation of the bio film of the mouth obstruction of kuoramusenshingu and/or with sterilization activity. In the feature of part, this invention at least formula of 1 types of effective quantity with respect to medical therapy (1) carbonate chemical compound and discloses the buccal cavity CARE composition which at least includes the shape medicine of 1 types:Here, R1 and R2 becoming independent, is following ones: Aliphatic basis Hydroxy aliphatic basis Or aryl basis. In the feature of part, this invention being the method of offering the buccal cavity CARE profit, at least formula of 1 types of effective quantity with respect to medical therapy (1) carbonate chemical compound and discloses the method of including the fact that the buccal cavity CARE composition which at least includes the shape medicine of 1 types is applied in the buccal cavity. In the feature of part, this invention, the tooth lap the metabolite of the disease upper part control or the lower part being the method of controlling, at least formula of 1 types of effective quantity with respect to medical therapy (1) carbonate chemical compound and discloses the method of including the fact that the buccal cavity CARE composition which at least includes the shape medicine of 1 types is applied in the buccal cavity.< Selective figure >It is not本発明は、クオラムセンシングの阻害および/または殺菌活性により口のバイオフィルムの成長および形成を阻害するための口腔ケア組成物および方法を含む。一部の態様において、本発明は療法上有効量の少なくとも1種類の式(1)のカーボネート化合物および少なくとも1種類の賦形剤を含む口腔ケア組成物を開示する:ここで、R1およびR2は独立して次のものである:脂肪族基;ヒドロキシ脂肪族基;またはアリール基。一部の態様において、本発明は、口腔ケアの利益を提供する方法であって、口腔に療法上有効量の少なくとも1種類の式(1)のカーボネート化合物および少なくとも1種類の賦形剤を含む口腔ケア組成物を適用することを含む方法を開示する。一部の態様において、本発明は、歯周疾患の代謝産物を上方制御または下方制御する方法であって、口腔に療法上有効量の少なくとも1種類の式(1)のカーボネート化合物および少なくとも1種類の賦形剤を含む口腔ケア組成物を適用することを含む方法を開示する。【選択図】なし
