The effective quantity of the salt which substantially, is displayed with formula (ii) and desirably exceeding pH8, the alkaline reaction component or the salt of 2 value metal cations which you keep, and it consists of one medicine shape medicine at least, the salt aforementioned formula (ii) at least 3 years, during room temperature storage, the stability which features that substantially it is stability the solid medicine composition. The process which is stabilized the salt formula (ii) and the process which produces the crystal salt and the crystal salt formula (ii).< Conversion 10 >実質的に、式(II)で表される塩の有効量および好ましくはpH8を超えて保持するアルカリ性反応成分または2価金属カチオンの塩、および少なくとも1つの医薬賦形剤からなり、前記式(II)の塩は、少なくとも3年、室温貯蔵の間、実質的に安定であることを特徴とする安定な固体医薬組成物。式(II)の塩を安定化させるプロセス、式(II)の結晶塩および結晶塩を製造するプロセス。【化10】
