BANIN, EYAL,REUBINOFF, BENJAMIN EITHAN,BOHANA-KASHTAN, OSNAT,NETZER, NIR,IRVING, CHARLES SHERARD
申请号:
CA2972700
公开号:
CA2972700A1
申请日:
2015.04.30
申请国别(地区):
CA
年份:
2016
代理人:
摘要:
A method of treating a subject with dry-form age-related macular degeneration (AMD) is disclosed. The method comprises administering into the subretina of the subject a therapeutically effective amount of a pharmaceutical composition comprising human RPE cells, wherein at least 95 % of the cells thereof co-express premelanosome protein (PMEL17) and cellular retinaldehyde binding protein (CRALBP), wherein the trans-epithelial electrical resistance of the cells is greater than 100 ohms to the subject, thereby treating the subject.