BANIN, Eyal,REUBINOFF, Benjamin Eithan,BOHANA-KASHTAN, Osnat,NETZER, Nir,IRVING, Charles Sherard
申请号:
PH12017501217
公开号:
PH12017501217A1
申请日:
2017.06.29
申请国别(地区):
PH
年份:
2018
代理人:
摘要:
A method of treating a subject with dry-form age-related macular degeneration (AMD) is disclosed. The method comprises administering into the subretina of the subject a therapeutically effective amount of a pharmaceutical composition comprising human RPE cells, wherein at least 95 pcnt of the cells thereof co-express premelanosome protein (PMEL17) and cellular retinaldehyde binding protein (CRALBP), wherein the trans-epithelial electrical resistance of the cells is greater than 100 ohms to the subject, thereby treating the subject.