RENGARAJAN JYOTHI,ADEKAMBI TOIDI,IBEGBU CHRISTIAN C
申请号:
IN201617039882
公开号:
IN201617039882A
申请日:
2016.11.22
申请国别(地区):
IN
年份:
2017
代理人:
摘要:
+This disclosure relates to methods of treating and diagnosing a tuberculosis infection as pulmonary active or latent based on biomarkers expressed on pools of CD4 cells. In certain embodiments the disclosure relates to methods of treatment of a subject diagnosed with tuberculosis comprising the steps of measuring a pool of CD4 IFN cells for cells that also express CD38 HLA DR and/or Ki 67 providing a measurement associating an increased measurement of CD4 IFN cells that also express CD38 HLA DR Ki 67 compared to a control as an indication that the subject has active tuberculosis and treating the subject with an aggressive tuberculosis treatment.