Disclosed are devices for urine voiding postponement, and methods for treatingconditions such as central diabetesinsipidus, enuresis, nocturia, urinary frequency or incontinence. The devicesdeliver a desmopressin flux through the skin of a patientin a low dose amount just necessary to achieve a desired anti-diuretic effectwithout undesirable side effects such as hyponatremia.The devices are designed to permit a state of normal urinary production toreturn quickly after the desmopressin flux is terminated.