Disclosed are devices for urine voiding postponement, and methods for treatingconditions such as central diabetes insipidus, enuresis, nocturia, urinaryfrequency or incontinence. The devices deliver a desmopressin flux throughthe skin of a patient in a low dose amount just necessary to achieve a desired anti-diureticeffect without undesirable side effects such as hyponatremia. The devices aredesigned to permit a state of normal urinary production to return quickly afterthe desmopressin flux is terminated.