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TETRAHYDRO-PYRIDO[3,4-b]INDOLE ESTROGEN RECEPTOR MODULATORS AND USES THEREOF
专利权人:
Genentech; Inc.
发明人:
Sharada Labadie,Jun Li,Jun Liang,Daniel Fred Ortwine,Xiaojing Wang,Jason Zbieg,Birong Zhang,Nicholas Charles Ray,Simon Goodacre,Zhiguo Liu,Tao Wang
申请号:
US15623884
公开号:
US20170362228A1
申请日:
2017.06.15
申请国别(地区):
US
年份:
2017
代理人:
摘要:
Described herein are tetrahydro-pyrido[3,4-b]indol-1-yl compounds with estrogen receptor modulation activity or function having the Formula I structure:and stereoisomers, tautomers, or pharmaceutically acceptable salts thereof, and with the substituents and structural features described herein. Also described are pharmaceutical compositions and medicaments that include the Formula I compounds, as well as methods of using such estrogen receptor modulators, alone and in combination with other therapeutic agents, for treating diseases or conditions that are mediated or dependent upon estrogen receptors.
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