Procédé pour la preparation de pyrimidine-diones fusionnés utilisés comme modulateurs du TRPA1

• 收藏
• 分享

专利权人:

Glenmark Pharmaceuticals S.A.

发明人:

申请号：

EP13005523.9

公开号：

EP2708538A1

申请日:

2010.03.17

申请国别(地区):

EP

年份:

2014

代理人:

摘要：

The present invention relates to a process for preparing a compound of formula (Id-1)or a pharmaceutically acceptable salt thereof, which comprisesreacting a compound of formula (35) with amine compound of formula (18)wherein,R1 and R2, which may be same or different, are independently selected from hydrogen and substituted or unsubstituted alkyl；U is substituted or unsubstituted heterocycles selected from thiazole and isoxazole； andV is substituted or unsubstituted aryl.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/