Maria Emilia Di Francesco;Andrew M. Haidle;John Michael Ellis;Liping Wang;Michael D. Altman;Ryan D. Otte;Kaleen Konrad Childers;Alan B. Northrup
发明人:
Michael D. Altman,Maria Emilia Di Francesco,Andrew M. Haidle,Ryan D. Otte,John Michael Ellis,Kaleen Konrad Childers,Alan B. Northrup,Liping Wang
申请号:
US14116205
公开号:
US09120785B2
申请日:
2012.05.04
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The present invention provides novel pyrimidine amines of formula I which are potent inhibitors of spleen tyrosine kinase, and are useful in the treatment and prevention of diseases mediated by said enzyme, such as asthma, COPD, rheumatoid arthritis, and cancer.