A method for preparing a lycium ruthenicum extract comprises the following steps: pulverizing lycium ruthenicum fruits, adding water into the pulverized lycium ruthenicum fruits to mix evenly, putting the mixture in a sealed state for 1 to 3 days, air-drying the mixture in an indoor temperature, carrying ultrasonic extraction by sequentially using hydrochloric acid, citric acid and noxalic acid, the extraction temperature ranging from 65ºC to 75ºC, and the time of a single ultrasonic extraction ranging from 1 h to 2 h merging the extracted liquids carrying filtering when the merged extracted liquids are hot, and feeding the product into a centrifugal machine to carry out centrifugation, the rotation speed of the centrifugal machine being 3000 r/min to 5000 r/min, and the centrifugation time ranging from 24 min to 45 min collecting the supernatant and feeding the supernatant into a chromatographic column filled with macroporous resin to perform adsorption and sequentially carrying out elution by sequentially adding water and elution liquid and feeding the product into a rotary evaporator for concentration, the concentration temperature ranging from 55ºC to 65ºC and carrying out drying to obtain the lycium ruthenicum extract. The preparation method has a simple process, low costs and very high extraction efficiency.Linvention concerne un procédé de préparation dun extrait de Lycium ruthenicum comprenant les étapes suivantes : pulvérisation de fruits de Lycium ruthenicum, addition deau aux fruits de Lycium ruthenicum pulvérisés en vue dun mélange homogène, isolement du mélange à labri de lair pendant 1 à 3 jours, séchage à lair du mélange à température ambiante, extraction par ultrasons à laide, successivement, dacide chlorhydrique, dacide citrique et dacide noxalique, la température dextraction étant comprise entre 65 °C et 75 °C, et la durée dune seule extraction par ultrasons variant de 1 h à 2 h regroupement des liquides extraits mise en œuvre dune filtration lor
