A cover for a stethoscope to prevent microbes from transferring from a patient to a stethoscope is disclosed. In one embodiment, a stethoscope cover comprises an antimicrobial barrier having a first and second surface, image forming material disposed on the antimicrobial barrier first surface, and an adhesive layer disposed on the second surface of the antimicrobial barrier to attach the antimicrobial barrier to a stethoscope. In some embodiments, the image forming material is configured to depict an image of a product. In some embodiments, the image forming material is configured to depict an image of an animal or character, to evoke feelings of happiness in a young patient.