The Brigham and Women's Hospital, Inc.;Massachusetts Institute of Technology
发明人:
Robert S. Langer,Carlo Giovanni Traverso,Alex G. Abramson,David Dellal
申请号：
US16415417
公开号：
US20200009371A1
申请日:
2019.05.17
申请国别(地区):
US
年份:
2020
代理人:
摘要：
Self-righting articles, such as self-righting capsules for administration to a subject, are generally provided. In some embodiments, the self-righting article may be configured such that the article may orient itself relative to a surface (e.g., a surface of a tissue of a subject). The self-righting articles described herein may comprise one or more tissue engaging surfaces configured to engage (e.g., interface with, inject into, anchor) with a surface (e.g., a surface of a tissue of a subject). In some embodiments, the self-righting article may have a particular shape and/or distribution of density (or mass) which, for example, enables the self-righting behavior of the article. In certain embodiments, the self-righting article a tissue-interfacing components. In some embodiments, each tissue-interfacing component may comprise an electrically-conductive portion configured for electrical communication with tissue and an insulative portion configured to not be in electrical communication with tissue.
