A portable telemetry device includes a measurement component, a wireless radio, a data communication component, and a voice communication component. The measurement component is configured to receive, from at least one sensor, physiological data representative of a physiological condition of a patient. The wireless radio is configured to wirelessly send and receive radio signals. The data communication component is configured to transmit the physiological data to a monitoring system using the wireless radio. The voice communication component is configured to provide, using the wireless radio, two-way voice communication between the portable telemetry device and medical staff at the monitoring system.