An endoscope apparatus includes an image pickup section equipped with a color separation section that picks up an image of returning light from a subject illuminated by an illumination section, an emphasis processing section that performs emphasis processing on sharpness of an image signal generated from the output signal of the image pickup section and a storage section that stores information for modifying processing contents of the emphasis processing, wherein the storage section stores information for setting image signals to be subjected to emphasis processing in first and second observation modes in which images are picked up under illumination of white light and narrow band light respectively to a luminance signal and a color difference signal, and the emphasis processing section performs emphasis processing on the luminance signal with a greater emphasis characteristic than the color difference signal over an entire frequency domain.