PROBLEM TO BE SOLVED: To provide a novel external preparation or internal preparation excellent in active oxygen elimination action, collagen degradation inhibitory action, melanin generation inhibitory action, and cell growth promoting action.SOLUTION: Hylotelephium cauticolum extract is excellent in active oxygen elimination action, collagen degradation inhibitory action, melanin generation inhibitory action, and cell growth promoting action, and is also excellent in stability. Hylotelephium cauticolum extract is used not only in a cosmetic field such as skin aging and whitening but also in a medical field such as inhibition of hypoactivity due to aging, prevention and treatment of cancer, and wound healing, and is expected to be applied to foods, cosmetics, quasi drugs, pharmaceuticals and the like.COPYRIGHT: (C)2015,JPO&INPIT【課題】活性酸素消去作用、コラーゲン分解抑制作用、メラニン生成抑制作用及び細胞増殖促進作用に優れた新規な外用剤又は内用剤を提供する。【解決手段】ヒダカミセバヤの抽出物は、優れた活性酸素消去作用、コラーゲン分解抑制作用、メラニン生成抑制作用及び細胞増殖促進作用を有し、安定性にも優れていた。ヒダカミセバヤの抽出物は、皮膚の老化や美白といった美容分野だけでなく、老化による機能低下の抑制、ガンの予防、治療や創傷治癒などといった医療分野にも利用ででき、食品、化粧品、医薬部外品及び医薬品等への応用が期待される。