1. It refers to the compound of 4 - (3-amino-phenyl) - 5,6-dihydro-4h - [1.3] oxazin-2-formula (I), wherein R1 is h, halogen or hydrocarbon (C1-C6)；R2 is h, asphalt (C1-C6) or halogen asphalt (C1-C3)；R3 is h or tar (C1-C6)；R4 is halogen, tar (C1-C6) or halogenated alcox (C1-C6)；R5 es-c (= O) - R6, wherein R6 is isomerization, cyclopentyl (C3-C6) or alternative isomerization. 1,4-phenyl [3]] - nitrogen [3]] - phenyl [3]] - nitrogen [3]] - phenyl 4]] - nitrogen [3]] - 5-cyano-pyridine-2-carbscillo, etc. He also mentioned an acquisition process and a drug synthesis. These compounds are inhibitors of bacilli and bacilli and can be used to treat Alzheimer's disease and type 2 diabetes.SE REFIERE A COMPUESTOS DERIVADOS DE 4-(3-AMINO-FENIL)-5,6-DIHIDRO-4H-[1,3]OXAZIN-2-ILAMINAS DE FORMULA (I) DONDE R1 ES H, HALOGENO O ALQUILO(C1-C6)； R2 ES H, ALQUILO(C1-C6) O HALOGENO-ALQUILO(C1-C3)； R3 ES H O ALQUILO(C1-C6)； R4 ES HALOGENO, ALQUILO(C1-C6) O HALOGENO-ALCOXI(C1-C6)； R5 ES -C(=O)-R6, EN DONDE R6 ES HETEROARILO, CICLOALQUILO(C3-C6) O HETEROCICLILO OPCIONALMENTE SUSTITUIDOS. SON COMPUESTOS PREFERIDOS: [3-((4R,5R)-2-AMINO-5-FLUOR-4-METIL-5,6-DIHIDRO-4H-[1,3]-OXAZIN-4-IL)-4-FLUOR-FENIL]-AMIDA DEL ACIDO 5-CLORO-PIRIDINA-2-CARBOXILICO； [3-((4R,5R)-2-AMINO-5-FLUOR-4-METIL-5,6-DIHIDRO-4H-[1,3]-OXAZIN-4-IL)-4-FLUOR-FENIL]-AMIDA DEL ACIDO 5-CIANO-PIRIDINA-2-CARBOXILICO； ENTRE OTROS. TAMBIEN SE REFIERE A UN PROCESO DE OBTENCION Y A UNA COMPOSICION FARMACEUTICA. DICHOS COMPUESTOS SON INHIBIDORES DE BACE1 Y BACE2 SIENDO UTILES EN EL TRATAMIENTO DE LA ENFERMEDAD DE ALZHEIMER, DIABETES TIPO 2
