Gaucher, Berangere,Desarbre, Eric,Page, Malcolm G. P.,Roussel, Patrick
申请号：
AU2012233003
公开号：
AU2012233003A1
申请日:
2012.09.28
申请国别(地区):
AU
年份:
2012
代理人:
摘要：
#$%^&*AU2012233003A120121018.pdf#####USEFUL COMBINATIONS OF MONOBACTAM ANTIBIOTICS WITH BETA-LACTAMASE INHIBITORS Abstract A pharmaceutical composition, comprising a combination of an antibiotically active 5 compound of the formula (1): with a -lactamase inhibitor of one of the formulae (II) to (XIII) are active against Gram-negative bacteria, in particular such bacteria which have become resistant against antibiotics such as aztreonam, carumonam and tigemonam. Optionally the compositions may comprise another p-lactamase inhibitor of one of the formulae (II) to (XIII), particularly of formula (V) or formula (VI). 10 R4 N'O R6 NR5 R3 ~ ~jR2 ,0 N O 'R1
