Eric Desarbre,Bérangère Gaucher,Malcom G. P. Page,Patrick Roussel
申请号:
US14512847
公开号:
US09346799B2
申请日:
2014.10.13
申请国别(地区):
US
年份:
2016
代理人:
摘要:
A pharmaceutical composition, comprising a combination of an antibiotically active compound of the formula (I): with a β-lactamase inhibitor of one of the formulae (II) to (XIII) are active against Gram-negative bacteria, in particular such bacteria which have become resistant against antibiotics such as aztreonam, carumonam and tigemonam. Optionally the compositions may comprise another β-lactamase inhibitor of one of the formulae (II) to (XIII), particularly of formula (V) or formula (VI).