COMPOSITIONS OF PIRFENIDONE / TOLL-LIKE RECEPTOR (TLR) ANTAGONISTS AND METHOD FOR THEIR USE TO STIMULATE THE PRODUCTION OF THE GRANULOCYTE COLONY STIMULATING FACTOR (G-CSF)
The invention disclosed herein relates to compositions and methods for treating subjects suffering from or at risk of developing neutropenia. In some embodiments, the methods comprise administering to a subject suffering from or at risk of developing neutropenia, an effective amount of pirfenidone and one or more toll-like receptor (TLR) agonists.