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超高速崩解錠劑及其製造方法
专利权人:
DAICEL CORPORATION
发明人:
HIRAMURA, TAKAHIRO,平邑隆弘,ITAYA, SAE,板谷左枝,HASHIKAWA, NAOHIRO,桥川尙弘,橋川尙弘,OKABAYASHI, TOMOHITO,冈林智仁,岡林智仁,SAKAGUCHI, ANAN,坂口阿南
申请号:
TW103123090
公开号:
TWI673069B
申请日:
2014.07.04
申请国别(地区):
TW
年份:
2019
代理人:
摘要:
An object of the present invention is to provide an orally disintegrating tablet (ultrafast-disintegrating tablet) having an extremely high disintegrability (short disintegration time), and a high tablet hardness, and to provide a simple method for the production of said ultrafast-disintegrating tablet without such a complicated process as freeze-drying. This invention relates to an orally disintegrating tablet comprising a first disintegrator component of an acid-type carboxymethylcellulose, and having a tablet hardness of 10 N or more and a disintegration time in water of less than 15 seconds, a method for the production of said orally disintegrating tablet, and to a disintegrative particulate composition for use in said method.提供一種具有極高崩解性(短崩解時間)且兼具高錠劑硬度的口腔內崩解錠劑(超高速崩解錠劑),及可不經冷凍乾燥等繁雜操作而製造此種超高速崩解錠劑的簡便方法。一種口腔內崩解錠劑、該口腔內崩解錠劑之製造方法及用於該製造方法之崩解性粒子組成物,該口腔內崩解錠劑係水中崩解時間未達15秒且錠劑硬度為10N以上之崩解性錠劑,含有由酸型羧甲基纖維素構成之第1崩解劑成分。
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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