PUKYONG NATIONAL UNIVERSITY INDUSTRY-UNIVERSITY COOPERATION FOUNDATION
发明人:
KIM, SE KWON,김세권,RYU, BO MI,류보미,S.W.A. HIMAYA,에스.더블유.에이. 히마야,ZHONG JI QIAN,중-지 첸
申请号：
KR1020100090197
公开号：
KR1020120028153A
申请日:
2010.09.14
申请国别(地区):
KR
年份:
2012
代理人:
摘要：
PURPOSE: A composition containing S. japonicus extract for anti-inflammation is provided to suppress LPS-induced iNOS and COX-1.CONSTITUTION: A method for preparing S. japonicus extract comprises: a step of extracting S. japonicus with methanol a step of filtering the extract to remove solvent and performing vacuum evaporation to obtain S. japonicus methanol extract a step of freeze-drying the extract and dissolving in distilled water and a step of fractioning using hexane, chloform, ethyl acetate, or butanol. A composition for anti-inflammation contains S. japonicus extract.COPYRIGHT KIPO 2012본 발명은 해삼을 메탄올로 추출한 후 유기용매로 분획추출하여 제조한 항-염증 활성을 갖는 해삼 추출물에 관한 것으로, 특히 아세트산에틸 분획 추출물이 LPS-유도 iNOS 및 COX-2 저해하여 우수한 항-염증 활성을 나타낸다.
