The present invention provides a compound Formula I or a pharmaceutically acceptable salt or a physiologically functional derivative thereof:. In addition, the prevent invention provides a pharmaceutical composition comprising the compound, and a method for treating or preventing receptor tyrosine kinases (RTKs)-related cancer with the compound.本發明提供一種式I之化合物或其醫藥上可接受之鹽類或其生理學上的功能衍生物:。 此外,本發明提供了包含該化合物之醫藥組合物,以及一種以該化合物治療或預防受體酪胺酸激酶(receptor tyrosine kinases,RTKs)相關癌症之方法。