Method for producing 7H-pyrrolo[2, 3-d]pyrimidine derivative and intermediate thereof

• 收藏
• 分享

专利权人:

Japan Tobacco Inc.

发明人:

Yamasaki, Takahiro,Hara, Yoshinori,Sakai, Takayuki,Murakami, Kengo,Hara, Katsuyoshi,Manta, Naoki

申请号：

AU2016289061

公开号：

AU2016289061A1

申请日:

2016.07.06

申请国别(地区):

AU

年份:

2017

代理人:

摘要：

The present invention provides: a method for producing a 7H-pyrrolo[2, 3-d]pyrimidine derivative that is useful as a janus kinase (JAK) inhibitor； an intermediate of the 7H-pyrrolo[2, 3-d]pyrimidine derivative； and a method for producing the intermediate. The present invention provides a method for producing 3-[(3S, 4R)-3-methyl-6-(7H-pyrrolo[2, 3-d]pyrimidin-4-yl)-1, 6-diazaspiro[3. 4]octan-1-yl]- 3-oxopropanenitrile, which uses a salt of an organic acid and (3S, 4R)-3-methyl-1, 6-diazaspiro[3. 4]octan-1-carboxylic acid benzyl.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/