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CAPSULE DURE GASTRORÉSISTANTE
专利权人:
QUALICAPS CO., LTD.;クオリカプス株式会社
发明人:
OSAKI, Yoshiro,大崎芳朗,ASO, Makoto,麻生慎,UENO, Koki,上野皓輝
申请号:
JPJP2019/024713
公开号:
WO2019/245031A1
申请日:
2019.06.21
申请国别(地区):
JP
年份:
2019
代理人:
摘要:
The present invention provides a hard capsule that can be formed by means of a cold gelation process and comprises a hard capsule coating that is enterosoluble. Provided is an enteric hard capsule comprising a coating which contains (a) a first component and a second component or (b) contains a first component and a second component and further contains at least one component from among a third component and a fourth component, wherein: the first component is methylcellulose and/or hydroxypropyl methylcellulose having a viscosity value of 6 mPa·s or higher, the second component is an enterosoluble methacrylic acid copolymer, the third component is a water-insoluble alkyl (meth)acrylate copolymer and/or ethylcellulose, and the fourth component is at least one compound selected from the group consisting of plasticizers that are acceptable pharmaceutically and as food additives and surfactants; and when 100 mass% is the total mass of the first component, the second component, the third component, and the fourth component included in the coating, the ratio of the first component is 30–70 mass%, the ratio of the second component is 30–60 mass%, and the total of the ratios of the first component and the second component is 70 mass% or higher.La présente invention concerne une capsule dure qui peut être formée au moyen d'un procédé de gélification à froid et qui comprend un enrobage de capsule dure qui est entérosoluble. L'invention concerne une capsule dure gastrorésistante comprenant un enrobage qui contient (a) un premier composant et un second composant ou (b) contient un premier composant et un second composant et contient en outre au moins un composant sélectionné parmi un troisième composant et un quatrième composant, sachant que : le premier composant est de la méthylcellulose et/ou de l'hydroxypropylméthylcellulose dont la viscosité est de 6 mPa·s ou plus, le second composant est un copolymère d'acide méthacrylique entérosoluble, le troisième composant est un (mét
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