The present invention is directed to catheter balloons and balloon catheters with such catheter balloons coated with at least one layer containing at least one antiproliferative, immunosuppressive, anti-angiogenic, anti-inflammatory, anti-restenotic and/or anti-thrombotic agent and a top coat consisting of a polyvinyl alcohol—polyethylene glycol graft copolymer as well as the use of these balloon catheters for the prevention of restenosis.
