PROBLEM TO BE SOLVED: To provide a natural material that can promote MFAP-4 production, or can also promote the construction of ECM and elastic fiber.SOLUTION: A MFAP-4 production promoter comprises at least one selected from Semiaquilegia adoxoides, Rosmarinus officinalis, and Tilia europaea, and extract thereof as an active ingredient.SELECTED DRAWING: NoneCOPYRIGHT: (C)2016,JPO&INPIT【課題】MFAP-4産生を促進し、ECM及び弾性線維の構築を促進することができる天然由来素材の提供。【解決手段】ヒメウズ、ローズマリー及びセイヨウシナノキ、ならびにそれらの抽出物から選択される少なくとも1つを有効成分とするMFAP-4産生促進剤。【選択図】なし