Immunopharmaceutic Institute of Hefei Ruida Co.; Ltd.
发明人:
Zhigang Tian,Haiming Wei,Xiaohu Zheng,Rui Sun,Weihua Xiao,Dan Liu,Baoru Wang
申请号：
US16302883
公开号：
US20190322758A1
申请日:
2017.05.25
申请国别(地区):
US
年份:
2019
代理人:
摘要：
The present application provides an antibody or antibody fragment capable of binding to a lung-specific X protein and being used to treat a tumor, and a use thereof. The antibody or antibody fragment includes heavy chain CDRs having amino acid sequences of SEQ ID NO: 1, SEQ ID NO: 2, and SEQ ID NO: 3 and light chain CDRs having amino acid sequences of SEQ ID NO: 4, SEQ ID NO: 5, and SEQ ID NO: 6. Alternatively, the antibody or antibody fragment includes heavy chain CDRs having amino acid sequences of SEQ ID NO: 1, SEQ ID NO: 7, and SEQ ID NO: 3 and light chain CDRs having amino acid sequences of SEQ ID NO: 8, SEQ ID NO: 5, and SEQ ID NO: 6. The antibody is a chimeric antibody.
