DUBOWCHIK, GENE M.,GUDMUNDSSON, OLAFUR S.,HAN, XIAOJUN,LAWRENCE, MICHAEL R.,LIPOVSEK, DASA,MADSEN, CORT S.,MAPELLI, CLAUDIO,MORIN, PAUL E.,MYERS, MICHAEL C.
申请号：
CA3052639
公开号：
CA3052639A1
申请日:
2018.02.08
申请国别(地区):
CA
年份:
2018
代理人:
摘要：
The present disclosure generally relates to modified relaxin polypeptides, such as modified human relaxin 2 polypeptides, comprising a non-naturally encoded amino acid which is linked to a pharmacokinetic enhancer, and therapeutic uses of such polypeptides, such as for the treatment of cardiovascular conditions (such as heart failure) and/or conditions relating to fibrosis.
