Dubowchik, Gene M.,Gudmundsson, Olafur S.,Han, Xiaojun,Lawrence, R. Michael,Lipovsek, Dasa,Madsen, Cort S.,Mapelli, Claudio,Morin, Paul E.,Myers, Michael C.
申请号：
AU2018219283
公开号：
AU2018219283A1
申请日:
2018.02.08
申请国别(地区):
AU
年份:
2019
代理人:
摘要：
The present disclosure generally relates to modified relaxin polypeptides, such as modified human relaxin 2 polypeptides, comprising a non-naturally encoded amino acid which is linked to a pharmacokinetic enhancer, and therapeutic uses of such polypeptides, such as for the treatment of cardiovascular conditions (such as heart failure) and/or conditions relating to fibrosis.
