Alakhov, Valery,Pietrzynski, Grzegorz,Patel, Kishore,Popek, Tomasz
申请号:
AU2019219792
公开号:
AU2019219792A1
申请日:
2019.08.21
申请国别(地区):
AU
年份:
2019
代理人:
摘要:
#$%^&*AU2019219792A120190912.pdf#####ABSTRACT The present invention is directed to pharmaceutical compositions including: (a) bendamustine, (b) a first charged cyclopolysaccharide, and optionally (c) a stabilizing agent which is a second charged cyclopolysaccharide having a charge opposite to that of the first charged cyclopolysaccharide. The composition provides unexpectedly desirable stability in reactive environments such as plasma, coupled with unexpectedly desirable anticancer activity. The compositions are suitable for injection or infusion into patients in need for treatment with bendamustine. 11