Merlin C. Thomas,Giorgio Zauli,Paola Secchiero,Bruno Fabris,Stella Bernardi
申请号：
US14002100
公开号：
US20140105898A1
申请日:
2012.02.27
申请国别(地区):
US
年份:
2014
代理人:
摘要：
This invention relates generally to methods and agents for modulating adiposity-related conditions. More particularly, the present invention relates to the use of TRAIL death receptor agonists, including nucleic acids such as TRAIL polynucleotides, peptides and polypeptides including TRAIL polypeptides, TRAIL DR agonist antigen-binding molecules, TRAIL DR peptide agonists as well as small molecule TRAIL DR agonists in compositions and methods for treating or preventing adiposity-related conditions such as obesity, diabetes mellitus and metabolic syndrome.
