COMBAL, JEAN PHILIPPE,LATOUR, ELISABETH,TAKRURI, HARUN
申请号：
NZ58427508
公开号：
NZ584275A
申请日:
2008.10.08
申请国别(地区):
NZ
年份:
2012
代理人:
摘要：
An aqueous ophthalmic formulation is disclosed, which comprises: (a) at least one cyclosporine having solubility in the formulation above about 28 microgram/mL (b) a surface active agent which is a polysorbate and (c) a nonionic tonicity agent which is a low molecular weight polyethylene glycol (PEG), which may be selected from the group consisting of PEG 200, PEG 300, PEG 400, and PEG 600 andwherein said aqueous formulation may further comprise: (d) one or more buffering agents and wherein the pH of the ophthalmic formulation is stable for at least 3 months and wherein said ophthalmic formulation may further comprises: (e) at least one corticosteroid.
