НИЛЬСЕН Бо Руд (DK),ШЕНФЕЛЬДТ Ларс (DK),МАДСЕН Нильс Йорген (DK)
申请号：
RU2012129844/15
公开号：
RU2012129844A
申请日:
2010.12.21
申请国别(地区):
RU
年份:
2014
代理人:
摘要：
1. A medical device comprising a hydrophilic coating, sterilized by contact with the medium swelling, comprising: a) a low molecular weight polyhydric alcohol and b) a separate buffer, selected from the group consisting of carboxylic acids, amino acids, aminosulfonic and inorganic kislot.2. The medical device of claim 1, wherein the medical device is a catheter with a hydrophilic pokrytiem.3. The medical device according to any one of claims 1 or 2, wherein the hydrophilic coating is a PVP-pokrytie.4. The medical device according to any one of claims 1 or 2, sterilized with oblucheniya.5. The medical device according to any one of claims 1 or 2, wherein the low molecular weight polyol has a molecular weight below 200 g / mol.6. The medical device according to any one of claims 1 or 2, wherein the low molecular weight polyhydric alcohol is present in the medium for swelling at a concentration of from 0.1% to 20% .7. The medical device according to any one of claims 1 or 2, wherein the low molecular weight polyhydric alcohol is glitserin.8. The medical device according to any one of claims 1 or 2, wherein separate buffer is nonpolymeric bufer.9. The medical device according to any one of claims 1 or 2, wherein separate buffer is a buffer of at least one value pKiz range from 2.7 to 5.10. The medical device according to any one of claims 1 or 2, wherein the buffer capacity - lower than 4 mM in the range from pH 4 to pH 7,4.11. The sterilized set comprising a medical device comprising a hydrophilic coating in contact with an aqueous liquid comprising: a) a low molecular weight polyhydric alcohol, and b) a separate buffer wherein said kit is sterilized using radiation while it is in contact with said1. Медицинское устройство, содержащее гидрофильное покрытие, стерилизованное при контакте со средой для набухания, включающей:а) низкомолекулярный многоатомный спирт иб) отдельный буфер, выбранный из группы, состоящей из карбоновых кислот, аминокислот, аминосульфоновых и неор
