Urs Beat Hagemann,Remko Albert Griep,Herald Reiersen,Sergej Michailovi{hacek over (c)} Kiprijanov
申请号：
US14515892
公开号：
US09458238B2
申请日:
2014.10.16
申请国别(地区):
US
年份:
2016
代理人:
摘要：
The present invention provides antibodies which bind to an epitope in the extracellular domain of human CC chemokine receptor 4 (CCR4) and which are capable of inhibiting the binding of macrophage-derived chemokine (MDC) and/or thymus and activation regulated chemokine (TARC) to CCR4. Also provided are inter alia immunoconjugates and compositions comprising such antibodies and methods and uses involving such antibodies, particularly in the medical and diagnostic fields.
