The present device and method is particularly suitable for a cooling infusion system, particularly for a cooling infusion system and more particular for fever treatment and/or normothermia and/or hypothermia. The device comprises at least one connection to a reservoir adapted to provide infusion fluid at least one temperature controller adapted to cool the temperature of the infusion fluid sufficiently so that the infusion fluid is delivered with a pre-set temperature at a temperature of between −1° C. and 14° C. at least one flow controller adapted to control the flow downstream the temperature controller in an average amount of between 100 ml/h and 8000 ml with an average flow rate of preferably 40 ml/h to 8000 ml/h and at least one output adapted to deliver the infusion fluid downstream the reservoir.
