ICOS RÉGULE DE FAÇON CRITIQUE L'EXPANSION ET LA FONCTION DES CELLULES INFLAMMATOIRES HUMAINES TH17

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专利权人:

THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA

发明人:

RILEY, JAMES, L.,PAULOS, CHRYSTAL,JUNE, CARL, H.,LEVINE, BRUCE

申请号：

EP11740423

公开号：

EP2531216A4

申请日:

2011.02.04

申请国别(地区):

EP

年份:

2013

代理人:

摘要：

The invention includes compositions and methods for generating and expanding therapeutic Th17 cells. The invention includes contacting T cells with a composition comprising a first agent that is capable of providing a primary activation signal to T cells and a second agent that is capable of activating ICOS on T cells in the presence of Th-17 polarizing agents.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/