Yi Fan;Yongqin Wan;Nathanael S. Gray;Dai Cheng;Pamela Albaugh;Yi Liu;Yuan Mi
发明人:
Yongqin Wan,Yuan Mi,Yi Fan,Dai Cheng,Yi Liu,Nathanael S. Gray,Pamela Albaugh
申请号：
US11718886
公开号：
US08101608B2
申请日:
2005.11.07
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The invention provides a novel class of compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with abnormal or deregulated kinase activity, particularly diseases or disorders that involve abnormal activation of the Abl, Bcr-Abl, cSrc, TPR-Met, Tie2, MET, FGFR3, Aurora, Axl, Bmx, BTK, c-kit, CHK2, Flt3, MST2, p70S6K, PDGFR, PKB, PKC, Raf, ROCK-II, Rsk1, SGK, TrkA, TrkB and TrkC kinases.
