PROBLEM TO BE SOLVED: To provide a novel aromatic carboxylic acid amide compound that has a blocking effect on TRPM8 which belongs to the melastatin subgroup of the TRP (transient receptor potential) channel superfamily and is effective as a medicine for prevention and treatment of various diseases in which the TRPM8 is involved, for example, chronic pain (preferably, neurological disorder due to cold allodynia or diabetic neuropathy).SOLUTION: Provided is a compound represented by the following formula.SELECTED DRAWING: NoneCOPYRIGHT: (C)2018,JPO&INPIT【課題】TRP(transient receptor potential)チャネルスーパーファミリーのメラスタチンサブグループに属するTRPM8に対する遮断効果を有し、該TRPM8が関与する各種疾患、例えば慢性疼痛(好ましくは冷アロディニアもしくは糖尿病性神経障害による神経障害性疼痛)、の予防・治療のための医薬として有用な新規芳香族カルボン酸アミド化合物の提供。【解決手段】下記式に代表される化合物。【選択図】なし
