The invention relates to polylactic acid materials containing surface modified magnesium particles and hydroxyapatite and a manufacturing method thereof. It comprises the steps of preparing magnesium particles and polylactic acid materials and adding the magnesium particles into an alkaline aqueous solution for treatment with a hydrothermal method at a temperature of 90-180℃ for 1-48 hours to form surface modified magnesium particles. Accordingly, the polylactic acid materials containing surface modified magnesium particles and hydroxyapatite can be used as biomedical materials so as to increase strength of biomedical materials, enhance compatibility with human cells, and achieve purposes of biodegradation and cell proliferation.本發明係有關於一種含表面改質鎂顆粒與氫氧基磷灰石之聚乳酸材料及其製造方法,所述方法包括準備一鎂顆粒與一聚乳酸材料;以及將鎂顆粒於一鹼性水溶液中,利用水熱法(hydrothermal method)於溫度90℃-180℃處理1-48小時,以產生表面改質之鎂顆粒;藉此,含表面改質鎂顆粒與氫氧基磷灰石之聚乳酸材料可應用生醫材料,並達到增進生醫材料強度、提升與人體細胞貼合度,以及具備生物降解與細胞增生之目的。無
