Marco Emgenbroich,Johannes Josef Leonhard,Kristina Kassner,Aurélia Lappert
申请号：
US15312433
公开号：
US20180221300A1
申请日:
2015.05.20
申请国别(地区):
US
年份:
2018
代理人:
摘要：
Transdermal therapeutic system for the transdermal administration of a systemically active agent comprising a self-adhesive layer structure, comprising A) a backing layer, and B) a dried biphasic layer, the dried biphasic layer having a) an outer phase having a composition comprising 75% to 100% of a polymer or polymer mixture, and b) an inner phase having a composition comprising at least one active agent, wherein the inner phase forms dispersed deposits in the outer phase, and c) 0.1% to 3.5% of an interface mediator with a kinematic viscosity of from 10 cSt to 100 000 cSt at 25° C., and and C) optionally an additional skin contact layer.
