Production of glycoproteins with reduced O-glycosylation

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专利权人:

GlycoFi; Inc

发明人:

Cook, James W.,Kett, Warren,Bobrowicz, Piotr

申请号：

AU2012203729

公开号：

AU2012203729B2

申请日:

2012.06.22

申请国别(地区):

AU

年份:

2014

代理人:

摘要：

#$%^&*AU2012203729B220140130.pdf#####PRODUCTION OF GLYCOPROTEINS WITH REDUCED 0GLYCOSYLATION Abstract A method is described for producing protein compositions having reduced amounts of 0- linked glycosylation. The method includes producing the protein in cells cultured in the presence of an inhibitor of Pmt-mediated 0-linked glycosylation and/or in the presence of one or more a-1,2mannosidases.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/