The present invention relates to a syringe with needle tip protection cover, which comprises a barrel, a pushing member, a needle, and a needle tip safety assembly. The barrel has a barrel first end and a barrel second end. The pushing member has a pushing end and is inserted in the barrel capable of moving relative to the barrel. The needle has a needle connector and a hollow tube communicated with each other. The needle connector is fixed at the barrel second end, and the hollow tube has a needle tip. The needle tip safety assembly is inserted in the hollow barrel body and the hollow tube capable of moving relative to them, and has a needle sheath portion. During the process of moving the pushing end from the barrel first end to the barrel second end, it will contact and push the needle tip safety assembly to make the needle sheath portion extending out of the hollow tube, so when the needle sheath portion exceeds the needle tip, the needle tip will be covered and prevented from contacting with outside. Therefore, the present invention has the advantages of automatic covering to enhance safety, enabling the needle tip safety assembly automatically directing toward the needle tip as a very special feature, and guiding assistance for covering direction.本發明係有關一種具針頭尖端保護蓋之注射針筒,其包括一筒體、一推壓元件、一針體及一針頭尖端安全組件。筒體具有一筒體第一端部及一筒體第二端部;推壓元件具有一推壓端部,並插設於筒體內而可與其相對移動。針體具有相連通的一針體接頭及一中空針管,針體接頭用以固定於筒體第二端部,中空針管具有一針頭尖端。針頭尖端安全組件插設於中空筒身與中空針管內,並可與其相對移動,針頭尖端安全組件具有一針頭遮套部。推壓端部從筒體第一端部移動至筒體第二端部的過程,係可接觸而推動針頭尖端安全組件,而使針頭遮套部伸出中空針管,並當超過針頭尖端時,係可遮蓋而防止針頭尖端對外接觸。故,本案兼具自動上蓋提高安全性、針頭尖端安全組件可自動朝向針頭尖端相當特別與具有上蓋方向導引輔助等優點。10‧‧‧筒體11‧‧‧中空筒身12‧‧‧筒體第一端部13‧‧‧筒體第二端部20‧‧‧推壓元件21‧‧‧推壓端部30‧‧‧針體31‧‧‧針體接頭32‧‧‧中空針管321‧‧‧針頭連接端322‧‧‧針頭尖端40‧‧‧針頭尖端安全組件41‧‧‧桿體42‧‧‧連結端部43‧‧‧針頭遮套部θ‧‧‧彎弧角