The present disclosure provides an endoprosthesis where a preferably polymeric coating has a number of surface features such as protrusions or textures that are arranged in a micropattern. The endoprosthesis optionally has an expanded state and a contracted state, and in some cases includes a stent with a polymeric coating attached to an outer surface of the stent. The stent may have an inner surface defining a lumen, an outer surface, and a stent thickness defined between the inner surface and outer surface. The stent may comprise a plurality of surface textures extending from the stent surfaces, wherein the textures are arranged in a macropattern.本發明提供其中較佳係聚合塗層具有多個排列成微圖案之表面特徵諸如突起或紋理的內置假體(endoprosthesis)。該內置假體視需要具有擴張狀態及收縮狀態,以及在一些情況中包括具有附著至支架之外表面的聚合塗層之支架。該支架可具有界定腔之內表面、外表面、及在該內表面與外表面之間界定的支架厚度。該支架可包含複數個從該等支架表面延伸的表面紋理,其中該等紋理係排列成巨圖案。