FANSLOW III, WILLIAM C.,凡斯罗 三世 威廉C,凡斯羅 三世 威廉C,KOZLOSKY, CARL,可洛斯其 卡尔,可洛斯其 卡爾,GUDAS, JEAN MARIE,古达斯 珍 马利,古達斯 珍 馬利
申请号:
TW102123128
公开号:
TW201420600A
申请日:
2013.06.27
申请国别(地区):
TW
年份:
2014
代理人:
摘要:
The present disclosure provides compositions and methods relating to antigen binding proteins, in particular, antibodies and bispecific antibodies which specifically bind to mesothelin. The disclosure provides nucleic acids encoding such antigen binding proteins and antibodies and methods of making and using such antibodies, including methods of treating and preventing cancer or other hypoproliferative disorders and related disorders by administering such antigen binding proteins and antibodies to a subject in need of such treatment.本發明提供與抗原結合蛋白質(特定言之特異性結合於間皮素之抗體及雙特異性抗體)有關之組合物及方法。本發明提供編碼該等抗原結合蛋白質及抗體之核酸,及製備及使用該等抗體之方法,包括藉由向需要治療之個體投與該等抗原結合蛋白質及抗體來治療及預防癌症或其他低增生性病症及相關病症之方法。