Mary J. Bossard,Cherie F. Ali,Xiaofeng Liu,Deborah H. Charych,Harold Zappe,Yujun Wang,Jicai Huang
申请号:
US15835125
公开号:
US20180085468A1
申请日:
2017.12.07
申请国别(地区):
US
年份:
2018
代理人:
摘要:
Conjugates of an interleukin-2 (“IL-2”) moiety and one or more nonpeptidic, water-soluble polymers are provided. Typically, the non-peptidic, water-soluble polymer is poly(ethylene glycol) or a derivative thereof. Also provided, among other things, are compositions comprising conjugates, methods of making conjugates, methods of administering compositions to an individual, nucleic acid sequences, expression systems, host cells, and methods for preparing IL-moieties.