Mary J. Bossard;Xiaofeng Liu;Cherie F. Ali;Deborah H. Charych;Yujun Wang
发明人:
Mary J. Bossard,Cherie F. Ali,Xiaofeng Liu,Deborah H. Charych,Yujun Wang
申请号:
US13884901
公开号:
US09861705B2
申请日:
2011.11.11
申请国别(地区):
US
年份:
2018
代理人:
摘要:
Conjugates of an interleukin-2 (“IL-2”) moiety and one or more nonpeptidic, water-soluble polymers are provided. Typically, the nonpeptidic, water-soluble polymer is poly(ethylene glycol) or a derivative thereof. Also provided, among other things, are compositions comprising conjugates, methods of making conjugates, methods of administering compositions to an individual, nucleic acid sequences, expression systems, host cells, and methods for preparing IL-moieties.