ARMER, RICHARD EDWARD,PETTIPHER, ERIC ROY,WHITTAKER, MARK,WYNNE, GRAHAM MICHAEL,VILE, JULIA,SCHROER, FRANK
申请号：
PL09702598
公开号：
PL2250161T3
申请日:
2009.01.19
申请国别(地区):
PL
年份:
2014
代理人:
摘要：
Compounds of general formula (I) wherein W is chloro or fluoro； R1 is phenyl optionally substituted with one or more substituents selected from halo, -CN, -C1-C6 alkyl, -SOR3, -SO2R3, -SO2N(R2)2, -N(R2)2, -NR2C(O)R3, -CO2R2, -CONR2R3, -NO2, -OR2, -SR2, -O(CH2)pOR2, and -O(CH2)p-O-(CH2)qOR2 wherein each R2 is independently hydrogen, -C1-C6 alkyl, -C3-C8 cycloalkyl, aryl or heteroaryl； each R3 is independently, -C1-C6 alkyl, -C3-C8 cycloalkyl, aryl or heteroaryl； p and q are each independently an integer from 1 to 3； and their pharmaceutically acceptable salts, hydrates, solvates, complexes or prodrugs are useful in orally administrable compositions for the treatment of allergic diseases such as asthma, allergic rhinitis and atopic dermatitis.
