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METHOD FOR SUPPRESSING OR PREVENTING FIBROUS ADHESION FORMATION USING A MULTICOMPONENT AQUEOUS OXYCHLORINE COMPOSITION PREPARED ON-SITE
专利权人:
发明人:
Robert D. Kross,Cleva Villanueva
申请号:
US13964457
公开号:
US20130323326A1
申请日:
2013.08.12
申请国别(地区):
US
年份:
2013
代理人:
摘要:
A composition and method are described for suppressing or preventing fibrous adhesion formation using a multicomponent aqueous oxychlorine composition. Fibrous adhesions typically form during healing of tissue, for example following a surgical procedure. A multicomponent oxychlorine composition is provided for irrigating the tissue which minimizes post-surgical adhesion formation, the composition containing both chlorine dioxide and chlorite ion, and a complex ion thereof. The chlorine dioxide level generally is in an effective range of ClO2 concentration from about 10 ppm to a maximum of about 110 ppm. In a preferred embodiment, a physiological composition is provided in a thickened form to increase retention in the area being treated. The composition is preferably based on a standard saline solution converted to the oxychlorine composition just prior to use by sequential addition of aqueous concentrates of a chlorite salt, a hypochlorite salt combined with a physiological buffer-producing salt of a multibasic acid, and an acidifying agent, optionally including a thickening agent.
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